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Bacterial meningitis

MedGen UID:
39048
•Concept ID:
C0085437
•
Disease or Syndrome
Synonyms: Bacterial Meningitides; Bacterial Meningitis; Meningitides, Bacterial; Meningitis, Bacterial
SNOMED CT: BM - Bacterial meningitis (95883001); Bacterial meningitis (95883001); Meningitis, bacterial (95883001)
 
Monarch Initiative: MONDO:0006670

Definition

Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection. [from NCI]

Professional guidelines

PubMed

Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients.
Cook AM, Morgan Jones G, Hawryluk GWJ, Mailloux P, McLaughlin D, Papangelou A, Samuel S, Tokumaru S, Venkatasubramanian C, Zacko C, Zimmermann LL, Hirsch K, Shutter L
Neurocrit Care 2020 Jun;32(3):647-666. doi: 10.1007/s12028-020-00959-7. PMID: 32227294Free PMC Article
Meningitis in adults: diagnosis and management.
Young N, Thomas M
Intern Med J 2018 Nov;48(11):1294-1307. doi: 10.1111/imj.14102. PMID: 30387309
ESCMID guideline: diagnosis and treatment of acute bacterial meningitis.
van de Beek D, Cabellos C, Dzupova O, Esposito S, Klein M, Kloek AT, Leib SL, Mourvillier B, Ostergaard C, Pagliano P, Pfister HW, Read RC, Sipahi OR, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB)
Clin Microbiol Infect 2016 May;22 Suppl 3:S37-62. Epub 2016 Apr 7 doi: 10.1016/j.cmi.2016.01.007. PMID: 27062097

Recent clinical studies

Etiology

Progress and Challenges in Bacterial Meningitis: A Review.
Hasbun R
JAMA 2022 Dec 6;328(21):2147-2154. doi: 10.1001/jama.2022.20521. PMID: 36472590
Global etiology of bacterial meningitis: A systematic review and meta-analysis.
Oordt-Speets AM, Bolijn R, van Hoorn RC, Bhavsar A, Kyaw MH
PLoS One 2018;13(6):e0198772. Epub 2018 Jun 11 doi: 10.1371/journal.pone.0198772. PMID: 29889859Free PMC Article
Community-acquired bacterial meningitis.
van de Beek D, Brouwer M, Hasbun R, Koedel U, Whitney CG, Wijdicks E
Nat Rev Dis Primers 2016 Nov 3;2:16074. doi: 10.1038/nrdp.2016.74. PMID: 27808261
ESCMID guideline: diagnosis and treatment of acute bacterial meningitis.
van de Beek D, Cabellos C, Dzupova O, Esposito S, Klein M, Kloek AT, Leib SL, Mourvillier B, Ostergaard C, Pagliano P, Pfister HW, Read RC, Sipahi OR, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB)
Clin Microbiol Infect 2016 May;22 Suppl 3:S37-62. Epub 2016 Apr 7 doi: 10.1016/j.cmi.2016.01.007. PMID: 27062097
Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis.
Brouwer MC, Tunkel AR, van de Beek D
Clin Microbiol Rev 2010 Jul;23(3):467-92. doi: 10.1128/CMR.00070-09. PMID: 20610819Free PMC Article

Diagnosis

Progress and Challenges in Bacterial Meningitis: A Review.
Hasbun R
JAMA 2022 Dec 6;328(21):2147-2154. doi: 10.1001/jama.2022.20521. PMID: 36472590
Acute bacterial meningitis.
Wall EC, Chan JM, Gil E, Heyderman RS
Curr Opin Neurol 2021 Jun 1;34(3):386-395. doi: 10.1097/WCO.0000000000000934. PMID: 33767093Free PMC Article
Acute Bacterial Meningitis.
Davis LE
Continuum (Minneap Minn) 2018 Oct;24(5, Neuroinfectious Disease):1264-1283. doi: 10.1212/CON.0000000000000660. PMID: 30273239
ESCMID guideline: diagnosis and treatment of acute bacterial meningitis.
van de Beek D, Cabellos C, Dzupova O, Esposito S, Klein M, Kloek AT, Leib SL, Mourvillier B, Ostergaard C, Pagliano P, Pfister HW, Read RC, Sipahi OR, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB)
Clin Microbiol Infect 2016 May;22 Suppl 3:S37-62. Epub 2016 Apr 7 doi: 10.1016/j.cmi.2016.01.007. PMID: 27062097
Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis.
Brouwer MC, Tunkel AR, van de Beek D
Clin Microbiol Rev 2010 Jul;23(3):467-92. doi: 10.1128/CMR.00070-09. PMID: 20610819Free PMC Article

Therapy

Progress and Challenges in Bacterial Meningitis: A Review.
Hasbun R
JAMA 2022 Dec 6;328(21):2147-2154. doi: 10.1001/jama.2022.20521. PMID: 36472590
Community-acquired bacterial meningitis.
van de Beek D, Brouwer MC, Koedel U, Wall EC
Lancet 2021 Sep 25;398(10306):1171-1183. Epub 2021 Jul 22 doi: 10.1016/S0140-6736(21)00883-7. PMID: 34303412
Acute bacterial meningitis.
Wall EC, Chan JM, Gil E, Heyderman RS
Curr Opin Neurol 2021 Jun 1;34(3):386-395. doi: 10.1097/WCO.0000000000000934. PMID: 33767093Free PMC Article
Meningitis.
Swanson D
Pediatr Rev 2015 Dec;36(12):514-24; quiz 525-6. doi: 10.1542/pir.36-12-514. PMID: 26628732
Corticosteroids for acute bacterial meningitis.
Brouwer MC, McIntyre P, Prasad K, van de Beek D
Cochrane Database Syst Rev 2015 Sep 12;2015(9):CD004405. doi: 10.1002/14651858.CD004405.pub5. PMID: 26362566Free PMC Article

Prognosis

Epidemiology of community-acquired bacterial meningitis.
Brouwer MC, van de Beek D
Curr Opin Infect Dis 2018 Feb;31(1):78-84. doi: 10.1097/QCO.0000000000000417. PMID: 29176349
Community-acquired bacterial meningitis.
Costerus JM, Brouwer MC, Bijlsma MW, van de Beek D
Curr Opin Infect Dis 2017 Feb;30(1):135-141. doi: 10.1097/QCO.0000000000000335. PMID: 27828810
Meningococcal pneumonia.
Vossen M, Mitteregger D, Steininger C
Vaccine 2016 Aug 17;34(37):4364-70. Epub 2016 Jul 18 doi: 10.1016/j.vaccine.2016.07.013. PMID: 27443594
Community-acquired bacterial meningitis in adults in the Netherlands, 2006-14: a prospective cohort study.
Bijlsma MW, Brouwer MC, Kasanmoentalib ES, Kloek AT, Lucas MJ, Tanck MW, van der Ende A, van de Beek D
Lancet Infect Dis 2016 Mar;16(3):339-47. Epub 2015 Dec 1 doi: 10.1016/S1473-3099(15)00430-2. PMID: 26652862
Neonatal bacterial meningitis.
Baud O, Aujard Y
Handb Clin Neurol 2013;112:1109-13. doi: 10.1016/B978-0-444-52910-7.00030-1. PMID: 23622318

Clinical prediction guides

Progress and Challenges in Bacterial Meningitis: A Review.
Hasbun R
JAMA 2022 Dec 6;328(21):2147-2154. doi: 10.1001/jama.2022.20521. PMID: 36472590
A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections.
Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD Jr, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN)
JAMA Pediatr 2019 Apr 1;173(4):342-351. doi: 10.1001/jamapediatrics.2018.5501. PMID: 30776077Free PMC Article
Global etiology of bacterial meningitis: A systematic review and meta-analysis.
Oordt-Speets AM, Bolijn R, van Hoorn RC, Bhavsar A, Kyaw MH
PLoS One 2018;13(6):e0198772. Epub 2018 Jun 11 doi: 10.1371/journal.pone.0198772. PMID: 29889859Free PMC Article
Clinical features and prognostic factors in adults with bacterial meningitis.
van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M
N Engl J Med 2004 Oct 28;351(18):1849-59. doi: 10.1056/NEJMoa040845. PMID: 15509818
Dexamethasone in adults with bacterial meningitis.
de Gans J, van de Beek D; European Dexamethasone in Adulthood Bacterial Meningitis Study Investigators
N Engl J Med 2002 Nov 14;347(20):1549-56. doi: 10.1056/NEJMoa021334. PMID: 12432041

Recent systematic reviews

Shorter versus longer duration of antibiotic treatment in children with bacterial meningitis: a systematic review and meta-analysis.
Sudo RYU, Câmara MCC, Kieling SV, Marques IR, Mesquita Y, Piepenbrink BE, Mari PC
Eur J Pediatr 2024 Jan;183(1):61-71. Epub 2023 Oct 23 doi: 10.1007/s00431-023-05275-8. PMID: 37870611
Global etiology of bacterial meningitis: A systematic review and meta-analysis.
Oordt-Speets AM, Bolijn R, van Hoorn RC, Bhavsar A, Kyaw MH
PLoS One 2018;13(6):e0198772. Epub 2018 Jun 11 doi: 10.1371/journal.pone.0198772. PMID: 29889859Free PMC Article
Streptococcus suis Meningitis: A Systematic Review and Meta-analysis.
van Samkar A, Brouwer MC, Schultsz C, van der Ende A, van de Beek D
PLoS Negl Trop Dis 2015;9(10):e0004191. Epub 2015 Oct 27 doi: 10.1371/journal.pntd.0004191. PMID: 26505485Free PMC Article
Corticosteroids for acute bacterial meningitis.
Brouwer MC, McIntyre P, Prasad K, van de Beek D
Cochrane Database Syst Rev 2015 Sep 12;2015(9):CD004405. doi: 10.1002/14651858.CD004405.pub5. PMID: 26362566Free PMC Article
Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures.
Ratilal BO, Costa J, Pappamikail L, Sampaio C
Cochrane Database Syst Rev 2015 Apr 28;2015(4):CD004884. doi: 10.1002/14651858.CD004884.pub4. PMID: 25918919Free PMC Article

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